There's a Manchester comedian called Steve Harris who isn't well known outside the area. When I went to see him, the whole audience was completely creased up.
I haven't been able to find a very good example of him online. There's this badly-recorded sketch from a local low-budget comedy club (N.B: Not for the easily offended!):
He can be a lot funnier than this, though, if what I saw is anything to go by.
Also, there's John Cooper Clarke, of course. More of a punk poet than a comedian, but fuckin' funny!
EDIT: Here's a link to a recording of 'Chickentown'.
'Bloody colour scheme is brown. Evidently Chickentown.'